Elevated D-Dimer can be seen in which clinical scenario?

Elevated D-Dimer can be seen in which clinical scenario?

• A. Chronic anemia
• B. Dehydration
• C. Postoperative state with clot breakdown
• D. Hypoglycemia

Answer: (C)

D-dimer is a fragment produced when cross-linked fibrin is broken down by plasmin during clot dissolution. An elevated D-dimer signals recent or ongoing coagulation with fibrinolysis. After surgery, tissue injury triggers clot formation to control bleeding, and as healing progresses these clots are broken down, raising D-dimer levels. The other options don’t involve this notable clot turnover—chronic anemia, dehydration, and hypoglycemia aren’t linked to increased fibrin degradation—so they wouldn’t typically cause an elevated D-dimer.

D-dimer is a fragment produced when cross-linked fibrin is broken down by plasmin during clot dissolution. An elevated D-dimer signals recent or ongoing coagulation with fibrinolysis. After surgery, tissue injury triggers clot formation to control bleeding, and as healing progresses these clots are broken down, raising D-dimer levels. The other options don’t involve this notable clot turnover—chronic anemia, dehydration, and hypoglycemia aren’t linked to increased fibrin degradation—so they wouldn’t typically cause an elevated D-dimer.